Fighting Inflammation and Infection with Stem Cells - Stem Cell Centers, Regenerative Stem Cell Therapy

Fighting Inflammation and Infection with Stem Cells

Research and Stem Cell Use for Dentistry
September 1, 2018
stem cells healing
Can the Body Heal without Stem Cells?
September 18, 2018
wound healing

wound healing

Do you have painful aches and pains from arthritis or other chronic conditions? Inflammation causes chronic conditions to worsen and can even shorten a person’s lifespan. However, stem cells are naturally anti-inflammatory and can help with chronic pain. They even have the potential to help patients regenerate their cells and tissues. If you have chronic inflammation, infections, pain and more, see how stem cells can help you!

The Danger of Chronic Inflammation

Not all inflammation is bad. We tend to think of inflammation as a physiological response that should be avoided, but it is the body’s natural, appropriate response for helping with the healing of injured tissues. The chemical signals that a damaged tissue releases communicate with the body so that white blood cells can work to rebuild tissues and repair the injured areas. Inflammation should cease when the healing process ends, but in some cases, the inflammation persists.

 

Chronic inflammation describes a state when the body instigates the inflammatory process even though there is no injury present. Why this happens is not always clear. Sometimes the a lingering infection can cause this, diet can cause this and some autoimmune diseases can as well. The problem with chronic inflammation is that it can lead to more serious issues like cancer.

Why Are Mesenchymal Stem Cells (MSCs)  Effective for Inflammation?

MSCs have been shown to prevent overactive immune responses from occurring, thus lowering inflammatory responses while allow the cell repair process to continue. MSCs also all fend off microbial invaders that could create new damage and infections to body tissues.

Why are MSCs so Helpful with Inflammation and Infection?

These stem cells release inflammation inhibitors along with growth signals that protect the tissues from extensive inflammation. MSCs work to repair cellular damage while dividing and replacing missing cells and augmenting blood flow to prevent a pile-up of damage signals. Stem cells are also able to help stop apoptosis–cell death that occurs because of a weakened cellular environment.

“Mesenchymal stem cells are important immunoregulatory cells in the body, because they respond to inflammation by homing to affected tissues and then controlling inflammation locally at that site. An essential characteristic of MSCs is their expression of a variety of chemokine and cytokine receptors that can home to the sites of inflammation by migrating towards inflammatory chemokines and cytokines”, writes WoundsResearch.com.

The National Institutes of Health has show in recent studies that topical administration of MSC can improve wound healing and infection control. Their published studies have shown the success that MSCs have had for managing acute infections, like pneumonia and sepsis, in mouse infection models.

Common Inflammatory Disease that Respond to MSCs

While there are many applications for MSCs for treating chronic inflammation and infection, there are some conditions where MSCs could make the biggest difference. These conditions include: multiple sclerosis, scleroderma,  rheumatoid arthritis, fibromyalgia, systemic lupus erythematosus, osteoarthritis, Crohns’s Disease, Ulcerative Colitis and others.

Reducing the Need for Anti-Inflammatory Drugs

MSCs offer a better alternative for treating inflammation then anti-inflammatory drugs and all their negative side effects. MSCs help control the damage signals from firing unnecessarily thus preventing inflammation from occurring at a chronic level–something those suffering from autoimmune diseases are far too familiar with. Mesenchymal stem cells can repair tissue damage as well as prevent it where systemic immunosuppressive drugs cannot.

The Future of Wound Care

Currently, the wound care industry produces a vast amount of products, dressings, and devices to treat wounds and infections. More recently, scaffoldings and cell-based therapies have also been added to traditional therapies, according to the National Institutes of Health (NIH), with stem cells offering a new therapeutic option that drastically different from current treatment options.

“MSCs can be deployed within scaffoldings, topically or by injection, to sense the microenvironment and influence the healing process in a more regenerative manner through paracrine functioning. With preactivation of MSCs, it is thought that fewer cells are required and that their paracrine effects are heightened,” writes the NIH.  

Many patients have received stem cell therapy and meta-analysis reports confirm that this type of wound care is safe.

Next Steps with MSCs and Wound Care

Scientists hope to propel wound care to a new level with off the shelf, genetically similar, activated MSCs that can be delivered in a biological scaffolding to support a more regenerative healing process.  The potential outcomes of this type of wound care would result in less scar tissue, increased strength, and reduced treatment costs, says the NIH.

Find Out How You Can Benefit from Stem Cell Therapy

Stem cell therapy is effective method for treating a myriad of conditions and diseases. Discover how you could benefit. To learn more, and to uncover what stem cell therapies you may currently be a candidate for, call Stem Cell Centers today at (877) 808-0016 and see what stem cell therapy can do for you!