Is There Research Showing Stem Cell Therapy Actually Works?
Stem cell therapy has garnished attention in the media because of the success it is having both nationally and internationally–in and out of the lab–but stem cells have been used by surgeons and doctors for more than 20 years.
Stem cells are undifferentiated cells that have the capacity to change into any specific cell type in the body. These cells once deployed to an area with injury or disease can readily change into the cell type that is needed. Moreover, stem cells home to sites of injury by cell signals that attract them to sites of injuries. Once they reach where they need to go, they dock and commence repairing the injury/disease by releasing cytokines, chemokines, and growth factors that aid in repair.
The healthcare community has benefited from the tissue regeneration outcomes in specialties such as surgery, orthopedics, pain management, burn care, eye, as well as dental. More recently, Podiatric Physicians have been effectively applying these allografts to patients with diabetic foot ulcers.
Stem cell injections have been growing in popularity over the past few decades Research and development have increased opportunities and discovered a variety of ground-breaking applications.
There are more than 200,000 peer-reviewed scientific publications on PubMed, with thousands discussing positive outcomes following the use of stem cells. Below is a brief discussion of some of the positive outcomes with the use of stem cells.
Mesenchymal stem cells (MSCs) are known to have the potential to regenerate articular cartilage. Studies have shown that intra-articular injection of stem cells provided improved knee function and less pain with no adverse events.
- Safety and Complications Reporting on the Re-implantation of Culture-Expanded Mesenchymal Stem Cells using Autologous Platelet Lysate Technique.
- Articular cartilage regeneration with autologous peripheral blood stem cells versus hyaluronic acid: a randomized controlled trial.
- Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells.
- Partial regeneration of the human hip via autologous bone marrow nucleated cell transfer: A case study.
- Regenerative medicine therapies utilize the anti-inflammatory properties of mesenchymal stem cells to alleviate inflammation-related osteoarthritis (OA) pain. In a 2011 study, for example, patients with severe OA were injected with mesenchymal stem cells and found they were able to walk longer without pain and climb a greater number of stairs after treatment. A follow-up study five years later showed that improvements had decreased, but that the knee that had received stem cell treatment was still better than at baseline. There are many other studies similar to this all supporting the notion that stem cells may be beneficial in treating arthritic conditions.
- Comparison of Cryopreserved Amniotic Membrane and Umbilical Cord Tissue with Dehydrated Amniotic Membrane/chorion Tissue
Growth Factors and Components:
- Growth Factor mRNA and Protein in Preserved Human Amniotic Membrane
- Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine
- Collagen Types in Normal and Prematurely Ruptured Amniotic Membranes
- Soluble Factors of Amnion-derived Cells in Treatment of Inflammatory and Fibrotic Pathologies
- Human Amnion-derived Stem Cells Have Immunosuppressive Properties on NK Cells and Monocytes
- Antibacterial Properties of Human Amnion and Chorion in Vitro
- Amniotic Fluid: Not Just Fetal Urine Anymore
Immune Evasive and Immune Privileged Properties:
- Amniotic Membrane-derived Stem Cells: Immunomodulatory Properties and Potential Clinical Application
- Immunogenicity of Human Amniotic Epithelial Cells After Transplantation into Volunteers
- Amnion-derived Multipotent Progenitor Cells Support Allograft Tolerance Induction
- Comparison of Angiogenic, Cytoprotective, and Immunosuppressive Properties of Human Amnion and Chorion-derived Mesenchymal Stem Cells
Pain Management and Anti-inflammatory Properties:
- Suppression of inflammatory and fibrotic responses in allergic inflammation by the amniotic membrane stromal matrix
- Amniotic Membrane and Amniotic Cells: Potential Therapeutic Tools to Combat Tissue Inflammation and Fibrosis
- Identification of Antiangiogenic and Anti-inflammatory Proteins in Human Amniotic Membrane
Joints and Cartilage:
National Institute of Health Supports the Research and Use of Stem Cells
According to the National Institute of Health, “Stem cells, directed to differentiate into specific cell types, offer the possibility of a renewable source of replacement cells and tissues to treat diseases including macular degeneration, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis.” The excitement around stem cells is their potential for treating common diseases like diabetes and heart disease because of their regenerative abilities.
How Does Stem Cell Therapy Work?
Stem cell therapy leverages your body’s ability to repair and heal itself. With stem cell therapy, your doctor injects stem cells into your body. (Not unlike receiving a cortisone or steroid shots). Stem cell injections have anti-inflammatory properties and offering you even more benefits than your standard injection therapies. Cortisone and other drugs can provide you with temporary pain relief, but stem cells actually restore your degenerated tissue WHILE providing pain relief. Following an injection, stem cells remain in the injured area for up to 24 months, constantly dividing and building new tissue. Stem cell injections contain hyaluronic acid, which lubricates joints and tendons, relieving your pain and restoring your mobility.
Stem Cell Therapy – Still Evolving
Stem cell therapy and research is still growing and evolving as scientists learn more and more about cells, regeneration and how to use cells for cell-based therapies to treat disease. Scientists use stem cells in the laboratory to screen new drugs and to create model systems to evaluate normal growth and discover the causes of birth defects. As technology and science continue to progress together, it is exciting to imagine where stem cells will take us in the coming years. The National Institute of Health stated that stem cells are promising candidates for tissue engineering and stem cell therapy of several human disorders. The best way you can learn more about the research and findings of stem cell therapy is to schedule a free consultation with a medical provider near you. Learn about the amazing potential of stem cells and if you are a candidate for stem cell therapy.
Are You a Candidate?
Keep Your Active Lifestyle, or get it back with Regenerative Stem Cell Therapy
If chronic knee, back, hip, shoulder pain, osteoarthritis, arthritis or other joint pain is limiting your daily routine or preventing you from activities you enjoy; stem cell therapy may be the answer you’ve been looking for!
Regenerative stem cell therapy offers exciting, long-term relief for people that are suffering from joint pain, arthritis, and neuropathy. The procedure takes less than 30 minutes with minimal pain and is extremely safe and effective. You can use the power of regenerative medicine to heal your body and return to the life and activities you love.